Composite Agency polymer analysis Assay,miRNA,peptide Synthesis, Properties, and Derivatization of Poly

Synthesis, Properties, and Derivatization of Poly


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Synthesis, Properties, and Derivatization of Poly(dihydrogermane): A Germanium-Based Polyethylene Analogue

Polygermanes are germanium-based analogues of polyolefins and possess polymer backbones made up catenated Ge atoms. In the present contribution we report the preparation of a germanium polyethylene analogue, polydihydrogermane (GeH2)n, via two straightforward approaches that involve topotactic deintercalation of Ca ions from the CaGe Zintl phase.

The resulting (GeH2)n possesses morphologically dependent chemical and electronic properties and thermally decomposes to yield amorphous hydrogenated Ge. We also show that the resulting (GeH2)n provides a platform from which functionalized polygermanes can be prepared via thermally induced hydrogermylation-mediated pendant group substitution.

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Polyethylene Glycol (PEG) Antibody

20-abx132170
  • EUR 439.00
  • EUR 133.00
  • EUR 1261.00
  • EUR 606.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

PEG 4000 (Polyethylene glycol)

PB0431 500g
EUR 63.05
  • Product category: Biochemicals/Biology Reagents/Other

PEG 6000 (Polyethylene glycol)

PB0432 500g
EUR 63.05
  • Product category: Biochemicals/Biology Reagents/Other

PEG 8000 (Polyethylene glycol)

PB0433 500g
EUR 63.05
  • Product category: Biochemicals/Biology Reagents/Other

Polyethylene Glycol (PEG) CLIA Kit

20-abx490560
  • EUR 9242.00
  • EUR 4920.00
  • EUR 1130.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-10x96wellstestplate 10x96-wells test plate
EUR 6040.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Polyethylene Glycol (PEG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-1x48wellstestplate 1x48-wells test plate
EUR 585.1
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Polyethylene Glycol (PEG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-1x96wellstestplate 1x96-wells test plate
EUR 793
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Polyethylene Glycol (PEG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-5x96wellstestplate 5x96-wells test plate
EUR 3268.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Polyethylene Glycol (PEG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

4-CEX163Ge
  • EUR 6091.00
  • EUR 3219.00
  • EUR 794.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Polyethylene Glycol elisa. Alternative names of the recognized antigen: PEO
  • POE
  • Polyethylene oxide
  • Polyoxyethylene
  • Carbowax
  • GoLYTELY
  • GlycoLax
  • Fortrans
  • TriLyte
  • Colyte
  • Halflytely
  • Macrogol
  • MiraLAX
  • MoviPrep
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Polyethylene Glycol (PEG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

General Polyethylene Glycol ELISA Kit (PEG)

RK00701 96 Tests
EUR 573

Polyethylene Glycol (PEG) Antibody (Biotin)

abx021052-005mg 0.05 mg
EUR 815
  • Shipped within 5-10 working days.

BSA Conjugated Polyethylene Glycol (PEG)

4-CPX163Ge11
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Inquire
  • Buffer composition: PBS, pH 7.4.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 62.1Da
  • Isoelectric Point: Inquire
Description: Recombinant Pan-species Polyethylene Glycol expressed in: E.coli

OVA Conjugated Polyethylene Glycol (PEG)

4-CPX163Ge21
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Inquire
  • Buffer composition: PBS, pH 7.4.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 62.1Da
  • Isoelectric Point: Inquire
Description: Recombinant Pan-species Polyethylene Glycol expressed in: E.coli

Polyethylene Glycol (PEG) Protein (BSA)

20-abx651925
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Polyethylene Glycol (PEG) Protein (OVA)

20-abx651926
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

ELISA kit for General PEG (Polyethylene Glycol)

ELK8264 1 plate of 96 wells
EUR 372
  • A monoclonal antibody specific to Polyethylene Glycol (PEG) has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled Polyethylene Glycol (PEG) and unlabeled Polyethylene Glycol (PEG) (Standards or sa
  • Show more
Description: A competitive Inhibition ELISA kit for detection of Polyethylene Glycol from General in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species)

4-PAX163Ge01
  • EUR 253.00
  • EUR 2615.00
  • EUR 649.00
  • EUR 319.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG)

Polyethylene glycol 4000

GX6931-100G 100 g
EUR 44

Polyethylene glycol 4000

GX6931-1KG 1 kg
EUR 62

Polyethylene glycol 4000

GX6931-500G 500 g
EUR 49

Polyethylene glycol 1000

GC0081-100G 100 g
EUR 46

Polyethylene glycol 8000

GC0902-100G 100 g
EUR 48

Polyethylene glycol 8000

GC0902-1KG 1 kg
EUR 77

Polyethylene glycol 8000

GC0902-500G 500 g
EUR 62

Polyethylene glycol 6000

GC2342-100G 100 g
EUR 44

Polyethylene glycol 6000

GC2342-1KG 1 kg
EUR 62

Polyethylene glycol 6000

GC2342-500G 500 g
EUR 49

Polyethylene glycol 400

GC3481-100G 100 g
EUR 41

Polyethylene glycol 400

GC3481-1KG 1 kg
EUR 65

Polyethylene glycol 400

GC3481-250G 250 g
EUR 46

Polyethylene glycol 400

GC3481-500G 500 g
EUR 53

Polyethylene glycol 400

GC3481-5KG 5 kg
EUR 153

Polyethylene glycol 300

GC9998-100G 100 g
EUR 40

Polyethylene glycol 300

GC9998-1KG 1 kg
EUR 62

Polyethylene glycol 300

GC9998-250G 250 g
EUR 44

Polyethylene glycol 300

GC9998-500G 500 g
EUR 52

Polyethylene glycol 300

GC9998-5KG 5 kg
EUR 142

Polyethylene glycol 1500

GK2627-100G 100 g
EUR 44

Polyethylene glycol 1500

GK2627-1KG 1 kg
EUR 62

Polyethylene glycol 1500

GK2627-500G 500 g
EUR 49

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), APC

4-PAX163Ge01-APC
  • EUR 355.00
  • EUR 3419.00
  • EUR 948.00
  • EUR 454.00
  • EUR 224.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with APC.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), Biotinylated

4-PAX163Ge01-Biotin
  • EUR 318.00
  • EUR 2565.00
  • EUR 753.00
  • EUR 391.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with Biotin.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), Cy3

4-PAX163Ge01-Cy3
  • EUR 432.00
  • EUR 4517.00
  • EUR 1223.00
  • EUR 564.00
  • EUR 257.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with Cy3.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), FITC

4-PAX163Ge01-FITC
  • EUR 304.00
  • EUR 2755.00
  • EUR 778.00
  • EUR 383.00
  • EUR 199.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with FITC.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), HRP

4-PAX163Ge01-HRP
  • EUR 324.00
  • EUR 2979.00
  • EUR 838.00
  • EUR 410.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with HRP.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), PE

4-PAX163Ge01-PE
  • EUR 304.00
  • EUR 2755.00
  • EUR 778.00
  • EUR 383.00
  • EUR 199.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with PE.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), APC-Cy7

4-PAX163Ge01-APC-Cy7
  • EUR 590.00
  • EUR 6718.00
  • EUR 1777.00
  • EUR 788.00
  • EUR 328.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with APC-Cy7.

D-alpha-Tocopherol polyethylene glycol succinate

GK2339-25G 25 g
EUR 150

D-alpha-Tocopherol polyethylene glycol succinate

GK2339-5G 5 g
EUR 70

HSP70 ELISA Kit (High-Sensitivity)

abx259904-96well 96 well
EUR 1083
  • Shipped within 5-12 working days.

HSP70 ELISA Kit (High-Sensitivity)

EK7109 96wells/kit, with removable strips.
EUR 758

HSP70 ELISA Kit (High-Sensitivity)

SKT-108-480 5 plates of 96 wells
EUR 2702
  • HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplas
  • Show more
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

HSP70 ELISA Kit (High-Sensitivity)

SKT-108-96 1 plate of 96 wells
EUR 685
  • HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplas
  • Show more
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

Human EGF ELISA Kit (High Sensitivity)

RK00024HS 96 Tests
EUR 587

OVAL High Sensitivity ELISA Kit (OKCD01353)

OKCD01353 96 Wells
EUR 596
Description: Description of target: Non-inhibitory serpin. Storage protein of egg white.;Species reactivity: pan-species;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: <28 pg/mL

ChromaFlash High-Sensitivity ChIP Kit

P-2027 48 Reactions
EUR 643.05
Description: Ask the seller for details

Human Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-010 1 Kit
EUR 712

Human Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-020 1 Kit
EUR 712

Mouse Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-030 1 Kit
EUR 712

Mouse Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-040 1 Kit
EUR 712

Monkey Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-050 1 Kit
EUR 712

Monkey Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-060 1 Kit
EUR 712

Rat Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-070 1 Kit
EUR 712

Rat Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-080 1 Kit
EUR 712

Poly(ethylene glycol) methyl ether (mPEG) Molecular Weight: 20000

PEG-20K 100 mg
EUR 225

Morphine antibody (High Sensitivity)

10-1379 1 mg
EUR 169
Description: Mouse monoclonal Morphine antibody

TMB Precipitating (High Sensitivity)

TM5125 125 ml
EUR 85

TMB Precipitating (High Sensitivity)

TM5500 500 ml
EUR 138

TMB Precipitating (High Sensitivity)

TM5999 1000 ml
EUR 208

High-sensitivity Human Growth Hormone ELISA Kit

DEIA449 96T
EUR 679
Description: Thishigh-sensitivity Human Growth Hormone ELISA Kit is to be used for the invitro quantitative determination of human growth hormone (hGH) concentrationsin serum.

Rat High Sensitivity Insulin (INS) ELISA Kit

abx363835-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

IGF1 High Sensitivity ELISA Kit (Dog) (OKCD01300)

OKCD01300 96 Wells
EUR 936
Description: Description of target: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca2+-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.;Species reactivity: Dog;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.5 pg/mL

Il10 High Sensitivity ELISA Kit (Mouse) (OKCD01301)

OKCD01301 96 Wells
EUR 870
Description: Description of target: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.43 pg/mL

Il1a High Sensitivity ELISA Kit (Mouse) (OKCD01303)

OKCD01303 96 Wells
EUR 909
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.03 pg/mL

Il1a High Sensitivity ELISA Kit (Rat) (OKCD01304)

OKCD01304 96 Wells
EUR 740
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.8 pg/mL

IL2 High Sensitivity ELISA Kit (Human) (OKCD01305)

OKCD01305 96 Wells
EUR 714
Description: Description of target: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.51 pg/mL

IL6 High Sensitivity ELISA Kit (Bovine) (OKCD01306)

OKCD01306 96 Wells
EUR 936
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.45 pg/mL

IL6 High Sensitivity ELISA Kit (Goat) (OKCD01307)

OKCD01307 96 Wells
EUR 1040
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Goat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.138 pg/mL

IL6 High Sensitivity ELISA Kit (Human) (OKCD01308)

OKCD01308 96 Wells
EUR 648
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.35 pg/mL

IL6 High Sensitivity ELISA Kit (Sheep) (OKCD01309)

OKCD01309 96 Wells
EUR 1027
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Sheep;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.46 pg/mL

Il6 High Sensitivity ELISA Kit (Rat) (OKCD01310)

OKCD01310 96 Wells
EUR 609
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.47 pg/mL

IL8 High Sensitivity ELISA Kit (Human) (OKCD01311)

OKCD01311 96 Wells
EUR 648
Description: Description of target: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.7 pg/mL

LN High Sensitivity ELISA Kit (Human) (OKCD01312)

OKCD01312 96 Wells
EUR 831
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

MMP1 High Sensitivity ELISA Kit (Rabbit) (OKCD01313)

OKCD01313 96 Wells
EUR 896
Description: Description of target: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. ;Species reactivity: Rabbit;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

MMP13 High Sensitivity ELISA Kit (Human) (OKCD01314)

OKCD01314 96 Wells
EUR 831
Description: Description of target: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.1;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 12.1 pg/mL

Mmp13 High Sensitivity ELISA Kit (Mouse) (OKCD01315)

OKCD01315 96 Wells
EUR 844
Description: Description of target: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 6.3 pg/mL

NGF High Sensitivity ELISA Kit (Human) (OKCD01316)

OKCD01316 96 Wells
EUR 727
Description: Description of target: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.97 pg/mL

Cxcl12 High Sensitivity ELISA Kit (Rat) (OKCD01317)

OKCD01317 96 Wells
EUR 896
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.5 pg/mL

TNF High Sensitivity ELISA Kit (Human) (OKCD01318)

OKCD01318 96 Wells
EUR 714
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.49 pg/mL

Coarse grained simulation of the aggregation and structure control of polyethylene nanocrystals 

Polyethylene (PE) telechelics with carboxylate functional groups at both ends have been shown to assemble into hexagonal nanocrystal platelets with a height defined by their chain length in basic CsOH-solution. In this coarse grained (CG) simulation study we show how properties of the functional groups alter the aggregation and crystallization behavior of those telechelics.

Systematic variation of the parameters of the CG model showed that important factors which control nanoparticle stability and structure are the PE chain length and the hydrophilicity and the steric demand of the head groups.

To characterize the aggregation process we analyzed the number and size of the obtained aggregates as well as intramolecular order and intermolecular alignment of the polymer chains. By comparison of CG and atomistic simulation data, it could be shown that atomistic simulations representing different chemical systems can be emulated with specific, different CG parameter sets.

Thus, the results from the (generic) CG simulation models can be used to explain the effect of different head groups and different counterions on the aggregation of PE telechelics and the order of the obtained nanocrystals.

Modelling the visual response to an OUReP retinal prosthesis with photoelectric dye coupled to polyethylene film 

Objective: Retinal prostheses have been developed to restore vision in blind patients suffering from diseases like retinitis pigmentosa. 

Approach: A new type of retinal prosthesis called the Okayama University-type Retinal Prosthesis (OUReP) was developed by chemically coupling photoelectric dyes to a polyethylene film surface. The prosthesis works by passively generating an electric potential when stimulated by light. However, the neurophysiological mechanism of how OUReP stimulates the degenerated retina is unknown. 

Main results: Here, we explore how the OUReP affects retinal tissues using a finite element model to solve for the potential inside the tissue and an active Hodgkin-Huxley model based on rat vision to predict the corresponding retinal bipolar response. 

Significance: We show that the OUReP is likely capable of eliciting responses in retinal bipolar cells necessary to generate vision under most ambient conditions.

Chitosan-Functionalized Recycled Polyethylene Terephthalate Nanofibrous Membrane for Sustainable On-Demand Oil-Water Separation

 The preservation of marine ecosystems is one of the most severe challenges at present. In particular, oil-water separation from oil spills and oily wastewater is important. For this reason, a low-cost, effective, and sustainable polymeric solution is in high demand. In this work, a controlled-wettability membrane for selective separation of oil-water mixtures and emulsions is developed. The nanofibrous membrane is prepared via a facile and cost-effective electrospinning technique using environmentally sustainable materials, such as recycled polyethylene terephthalate and chitosan.

The effect of different concentrations of chitosan on the morphology, chemical composition, mechanical properties, wettability, and separation performance of the membrane is evaluated. The membranes exhibited underoil superhydrophobic and underwater superoleophobic behavior, which is essential to perform the selective separation. In fact, the designed filter has competitive antifouling properties (oil intrusion pressure > 45 kPa) and showed high heavy- and light-oil/water separation efficiencies (>95%) both for emulsions and immiscible mixtures.

In vitro bio-interaction responses and hemocompatibility of Nano-based Linear Low-Density Polyethylene Polymer Embedded with Heterogeneous TiO 2/ZnO Nanocomposites for biomedical applications 

An innovative nano-base polymer that scavenges radicals and reactive oxygen species exhibits potential antibacterial properties, which are crucial in the biomedical field, particularly in reducing nosocomial infections. However, the safety of this nano-based polymer, which has direct contact with the human system, has not been fully understood. The present study investigated the cytocompatibility and hemocompatibility responses of linear low-density polyethylene polymer (LLDPE) embedded with difference ratios of heterogeneous TiO2/ZnO nanocomposites.

Exposure of the blood and fibroblast cells to LLDPE/100Z and LLDPE/25T75Z/10% nanocomposite films for 48 and 72 h decreased their viability by less than 40%, compared with LLDPE, LLDPE/100T and LLDPE/25T75Z/5% nanocomposite films. It also presented possible cellular damage and cytotoxicity, which was supported by the findings from the significant release of extracellular lactate dehydrogenase (LDH) profiles and cell survival assay Further observation using an electron microscope revealed that LLDPE films with heterogeneous 25T75Z/5% promoted cell adhesion.

Moreover, no hemolysis was detected in all ratios of heterogeneous TiO2/ZnO nanocomposite in LLDPE film as it was less than 0.2%, suggesting that these materials were hemocompatible. This study on LLDPE film with heterogeneous TiO2/ZnO nanocomposites demonstrated favorable biocompatible properties that were significant for advanced biomedical polymer application in a hospital setting.

Synthesis of novel polymeric nanoparticles (methoxy-polyethylene glycol-chitosan/hyaluronic acid) containing 7-ethyl-10-hydroxycamptothecin for colon cancer therapy: in vitro, ex vivo and in vivo investigation 

  • The goal of the current study was to target 7-ethyl-10-hydroxycamptothecin (SN38) orally to colon tumours by synthesizing a targeting polymer. To achieve the optimum delivery for SN38, initially methoxy-polyethylene glycol (mPEG)-chitosan was synthesized and then nanoparticles were developed through ionic gelation between mPEG-chitosan and hyaluronic acid as a ligand for cell-surface glycoprotein CD44 receptor.
  • The SN38 was loaded in nanoparticles (SN38-NPs) using the non-covalent physical adsorption method. The size of the optimized SN38-NPs was 226.7 nm, encapsulation efficiency was 89.23% and drug content was 7.98 ± 0.54% in the optimum formulation. The attachment of mPEG to chitosan was confirmed by proton nuclear magnetic resonance.
  • The results of differential scanning calorimetry and Fourier transforms infra-red analysis indicated that SN38 existed in amorphous form and functional groups of SN38 protected in the formulations which could be a sign of suitable encapsulation of SN38 in SN38-NPs. In vitro study indicated that SN38-NPs were more potent against the cancer cells than free SN38.
  • The cellular uptake of SN38-NPs improved up to 1.6-fold against human colorectal adenocarcinoma (Caco-2) cells. Moreover, SN38-NPs remarkably demonstrated superior anti-tumor efficacy in contrary to pure SN38. This suggests the advantage of SN38-NPs as a potent oral drug carrier which could be further explored for clinical investigations.

In-Plane Shear Strength of Single-Lap Co-Cured Joints of Self-Reinforced Polyethylene Composites

 The present study introduces the analysis of single-lap co-cured joints of thermoplastic self-reinforced composites made with reprocessed low-density polyethylene (LDPE) and reinforced by ultra-high-molecular-weight polyethylene (UHMWPE) fibers, along with a micromechanical analysis of its constituents. A set of optimal processing conditions for manufacturing these joints by hot-press is proposed through a design of experiment using the response surface method to maximize their in-plane shear strength by carrying tensile tests on co-cured tapes.

Optimal processing conditions were found at 1 bar, 115 °C, and 300 s, yielding joints with 6.88 MPa of shear strength. The shear failure is generally preceded by multiple debonding-induced longitudinal cracks both inside and outside the joint due to accumulated transversal stress. This composite demonstrated to be an interesting structural material to be more widely applied in industry, possessing extremely elevated specific mechanical properties, progressive damage of co-cured joints (thus avoiding unannounced catastrophic failures) and ultimate recyclability.

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